Acetohydroxamic Acid → Caracemide
反応式
[C:1]([NH:4][OH:5])(=[O:3])[CH3:2].[CH3:6][N:7]=[C:8]=[O:9]>C(N(CC)CC)C.C(Cl)Cl>[CH3:6][NH:7][C:8]([N:4]([O:5][C:8]([NH:7][CH3:6])=[O:9])[C:1](=[O:3])[CH3:2])=[O:9]参加物
5
実験手順
A mixture of acetohydroxamic acid (7.5 grams), methyl isocyanate (12.0 grams), 80 milliliters (ml) of methylene chloride, and about three drops of triethylamine were stirred together for about one hour in order to obtain solution. The solution was allowed to stand at room temperature overnight after which the solvent was removed under vacuum, leaving a residue. The residue was recrystallized from methylene chloride leaving the desired N-((methylamino)carbonyl)-N-(((methylamino)carbonyl)oxy)acetamide as white crystals having a melting point (m.p.) of 121°-123.5° C.
後処理
- customto obtain solution
- waitto stand at room temperature overnight
- customafter which the solvent was removed under vacuum
- customleaving a residue
- customThe residue was recrystallized from methylene chloride leaving the desired N-((methylamino)carbonyl)-N-(((methylamino)carbonyl)oxy)acetamide as white crystals
- customa melting point (m.p.) of 121°-123.5° C.
出典と根拠
- ORDレコード
- ord-bda5ec0b37944ff997791b0f58c60577
- 出典データセット
- uspto-grants-1983_11
- 特許番号
- US04413009
反応ノート
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