5H-Dibenzo[a,d]cyclohepten-5-one → dibenzo[a,d]cyclooctene-6,12(5H,7H)-dione

HRID 1648840

反応式

HRID 1648840 の反応式
C1C2C=CC3C=CC=CC=3C(=O)C=2C=CC=1.Br[C:18]1[CH:35]=[CH:34][C:21]2[CH2:22][C:23](=[O:33])[CH2:24][C:25]3[CH:32]=[CH:31][CH:30]=[CH:29][C:26]=3[C:27](=[O:28])[C:20]=2[CH:19]=1.ClC1C=CC2CC(=O)CC3C=CC=CC=3C(=O)C=2C=1.FC1C=CC2CC(=O)CC3C=CC=CC=3C(=O)C=2C=1>BrC1C=CC2C=CC3C=CC=CC=3C(=O)C=2C=1.ClC1C=CC2C=CC3C=CC=CC=3C(=O)C=2C=1.FC1C=CC2C=CC3C=CC=CC=3C(=O)C=2C=1.ClC1C=CC=CC=1Br>[O:33]=[C:23]1[CH2:22][C:21]2[CH:34]=[CH:35][CH:18]=[CH:19][C:20]=2[C:27](=[O:28])[C:26]2[CH:29]=[CH:30][CH:31]=[CH:32][C:25]=2[CH2:24]1

参加物

9

反応物 4

HCID 166795H-Dibenzo[a,d]cyclohepten-5-oneHCID 155809272-Bromo-6,12-dioxo-5,6,7,12-tetrahydrodibenzo[a,d]cycloocteneHCID 155809282-Chloro-6,12-dioxo-5,6,7,12-tetrahydrodibenzo[a,d]cycloocteneHCID 204808902-Fluoro-6,12-dioxo-5,6,7,12-tetrahydrodibenzo[a,d]cyclooctene

生成物 1

HCID 12552292dibenzo[a,d]cyclooctene-6,12(5H,7H)-dione

試薬・触媒・溶媒 4

HCID 127541-Bromo-2-chlorobenzene溶媒HCID 114830103-bromo-5H-dibenzo[a,d]cyclohepten-5-one溶媒HCID 126906103-Chloro-5H-dibenzo[A,D][7]annulen-5-one溶媒HCID 156285903-fluoro-5H-dibenzo[a,d]cyclohepten-5-one溶媒

実験手順

Employing the procedure substantially as described in Example 1, Steps A through D, but substituting for the 5H-dibenzo[a,d]cyclohepten-5-one used in Step A thereof an equimolecular amount of 3-bromo-5H-dibenzo[a,d]cyclohepten-5-one, 3-chloro-5H-dibenzo[a,d]cyclohepten-5-one, or 3-fluoro-5H-dibenzo[a,d]cyclohepten-5-one, and o-chlorobromobenzene as solvent in Step B, there are produced, respectively, 2-bromo-6,12-dioxo-5,6,7,12-tetrahydrodibenzo[a,d]cyclooctene, m.p. 133°-138° C., 2-chloro-6,12-dioxo-5,6,7,12-tetrahydrodibenzo[a,d]cyclooctene, m.p. 148°-149° C., and 2-fluoro-6,12-dioxo-5,6,7,12-tetrahydrodibenzo[a,d]cyclooctene.

出典と根拠

ORDレコード
ord-b06949016c6a4ab89e8f6bb23e25f2c2
出典データセット
uspto-grants-1983_11
特許番号
US04414154

関連ノート

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