Water → 2-Sulfamoyl-6-benzothiazolyl acetate

HRID 1649386ノート

反応式

HRID 1649386 の反応式
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10]([NH2:13])(=[O:12])=[O:11].O.O.[C:16]([O-:19])(=[O:18])[CH3:17].[Li+].[Cr](O[Cr]([O-])(=O)=O)([O-])(=O)=O.[K+].[K+].O>C(O)(=O)C.C([O-])(=O)C.[Pd+2].C([O-])(=O)C>[C:16]([O:19][C:7]1[CH:8]=[CH:9][C:4]2[N:3]=[C:2]([S:10](=[O:12])(=[O:11])[NH2:13])[S:1][C:5]=2[CH:6]=1)(=[O:18])[CH3:17]

参加物

7

反応物 4

HCID 962WaterHCID 24502Potassium DichromateHCID 679442-BenzothiazolesulfonamideHCID 23666338Lithium acetate dihydrate

生成物 1

HCID 132366622-Sulfamoyl-6-benzothiazolyl acetate

試薬・触媒・溶媒 2

HCID 167845palladium(II) acetate触媒HCID 176Acetic Acid溶媒

実験手順

A stirred solution of benzothiazole-2-sulfonamide (2.14 g, 0.01 mole), palladium acetate (2.25 g, 0.01 mole), lithium acetate dihydrate (1.65, 0.025 mole) and potassium dichromate (5.9 g, 0.02 mole) in acetic acid (25 ml) is heated on a steam bath for 24 hours then poured into H2O (100 ml) to give 2-sulfamoyl-6-benzothiazolyl acetate which melts at 193°-4° C. after recrystallization from 2-propanol.

出典と根拠

ORDレコード
ord-08a811ec83da470191a4a1c8cd779c04
出典データセット
uspto-grants-1983_11
特許番号
US04416890

反応ノート

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