Formic Acid → (1-Aminoethylidene)bisphosphonic acid

反応式

[C:1]([O-])(=O)[CH3:2].[NH4+:5].C(O)=O.O1P2[O:15][P:16]3[O:18]P(O2)OP1[O:17]3>>[NH2:5][C:1]([P:16]([OH:15])(=[O:17])[OH:18])([P:16]([OH:18])(=[O:15])[OH:17])[CH3:2]

参加物

反応物 3

HCID 284Formic Acid

HCID 1232902,4,6,8,9,10-Hexaoxa-1,3,5,7-tetraphosphatricyclo(3.3.1.13,7)decane

HCID 517165Ammonium Acetate

生成物 1

HCID 84770(1-Aminoethylidene)bisphosphonic acid収率 175.6%

実験手順

The procedure was as described in Example 1, but a blend of 40.5 g (0.525 mol) ammonium acetate and 23 g (0.5 mol) formic acid was reacted with 55 g (0.25 mol) P4O6. 45 g 1-aminoethane-1,1-diphosphonic acid was obtained.

出典と根拠

ORDレコード: ord-d6c6ef98f394482981ba5755adf272f0
出典データセット: uspto-grants-1983_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04418019

反応ノート

読み込み中…