1,3-Propanediamine → Anthraquinone, 1,4-bis(3-(aminopropyl)amino)-5,8-dihydroxy-

HRID 1649538

反応式

HRID 1649538 の反応式
[CH2:1]1[C:15](=[O:16])[C:14]2[C:5](=[C:6]([OH:20])[C:7]3[C:12]([C:13]=2[OH:17])=[C:11](O)[CH:10]=[CH:9][C:8]=3O)[C:3](=[O:4])[CH2:2]1.[NH2:21][CH2:22][CH2:23][CH2:24][NH2:25]>>[NH2:21][CH2:22][CH2:23][CH2:24][NH:25][C:8]1[C:7]2[C:6](=[O:20])[C:5]3[C:14](=[C:15]([OH:16])[CH:1]=[CH:2][C:3]=3[OH:4])[C:13](=[O:17])[C:12]=2[C:11]([NH:21][CH2:22][CH2:23][CH2:24][NH2:25])=[CH:10][CH:9]=1

参加物

3

反応物 2

HCID 4281,3-PropanediamineHCID 664859,10-Anthracenedione, 2,3-dihydro-1,4,5,8-tetrahydroxy-

生成物 1

HCID 167850Anthraquinone, 1,4-bis(3-(aminopropyl)amino)-5,8-dihydroxy-

反応条件

温度
45 °C

実験手順

A suspension of 10.0 g. of leuco-1,4,5,8-tetrahydroxyanthraquinone in 120 ml. of de-aerated 1,3-diaminopropane is stirred and heated at 45° C. under nitrogen for one hour and then for 10 minutes as air is bubbled into the suspension. The mixture is then evaporated to dryness and the residue is extracted with 650 ml. of ethanol in a Soxhlet apparatus for 17 hours. The extract is filtered while hot, concentrated to 95 ml. and then diluted with 900 ml. of diethyl ether. The mixture is cooled and the solid is collected, washed with ethanol-diethyl ether, then diethyl ether giving the desired product as 9.57 g. of a blue solid, mp. 115°-130° C.

後処理

  1. additionA suspension of 10.0 g
  2. customfor 10 minutes as air is bubbled into the suspension
  3. customThe mixture is then evaporated to dryness
  4. extractionthe residue is extracted with 650 ml
  5. filtrationThe extract is filtered while hot,
  6. concentrationconcentrated to 95 ml
  7. additionand then diluted with 900 ml
  8. temperatureThe mixture is cooled
  9. customthe solid is collected
  10. washwashed with ethanol-diethyl ether

出典と根拠

ORDレコード
ord-11405828e19f4a44979e99737edccbf3
出典データセット
uspto-grants-1983_11
特許番号
US04418078

関連ノート

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