HCID 14076002、化合物 → HCID 14076005、化合物

HRID 1649624ノート

反応式

HRID 1649624 の反応式
[CH3:1][C:2]([CH3:16])([C:4](=[O:15])[C:5]#[C:6][CH2:7][O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[CH3:3].[H][H]>CO.[Ni]>[CH3:3][C:2]([CH3:16])([C:4](=[O:15])[CH2:5][CH2:6][CH2:7][O:8][C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1)[CH3:1]

参加物

5

反応物 2

HCID 14076002HCID 14076002、化合物HCID 178418361HCID 178418361、化合物

生成物 1

HCID 14076005HCID 14076005、化合物収率 95.7%

試薬・触媒・溶媒 2

HCID 935Nickel触媒HCID 887Methanol溶媒

実験手順

20 g (0.0926 mol) of 2,2-dimethyl-6-phenoxy-hex-4-in-3-one are dissolved in 180 ml of methanol, and 5 g of Raney nickel are added. The mixture is hydrogenated with hydrogen under a pressure of 50 to 60 bar at 37° C. The hydrogenation has ended after 40 minutes. The reaction mixture is filtered and the filtrate is concentrated by stripping off the solvent under reduced pressure. 19.5 g (95.7% of theory) of 2,2-dimethyl-6-phenoxy-hexan-3-one are obtained in this manner.

後処理

  1. filtrationThe reaction mixture is filtered
  2. concentrationthe filtrate is concentrated

出典と根拠

ORDレコード
ord-36b585179e6b4d1b8db7f859de431403
出典データセット
uspto-grants-1990_05
特許番号
US04921529

反応ノート

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