Sodium Acetate → HCID 13730721、化合物
反応式
[C:1]([C:3]([NH:8][C:9](=[O:15])/[CH:10]=[CH:11]\[C:12]([OH:14])=O)([CH3:7])[CH:4]([CH3:6])[CH3:5])#[N:2].C([O-])(=O)C.[Na+]>C(OC(=O)C)(=O)C>[CH:4]([C:3]([CH3:7])([N:8]1[C:9](=[O:15])[CH:10]=[CH:11][C:12]1=[O:14])[C:1]#[N:2])([CH3:6])[CH3:5]参加物
4
実験手順
A solution of N-(1-cyano-1,2-dimethylpropyl)maleamic acid (595 g, 2.83 mol) in acetic anhydride (3.96 liters) containing sodium acetate (13.72 g, 0.167 mol) is heated under reflux for one hour, cooled and the solvent removed in vacuo. The product is distilled* at 120°-130° C./0.1 mm to give 337 g (63%) of product. *The pot temperature should not excede 200°. Anal. calcd. for C10H12N2O2 : C, 62.49; H, 6.29; N, 14.57. Found: C, 62.32; H, 6.36; N, 14.59.
後処理
- temperatureis heated
- temperatureunder reflux for one hour
- temperaturecooled
- customthe solvent removed in vacuo
- customis distilled* at 120°-130° C.
出典と根拠
- ORDレコード
- ord-5a593657b6ce4ceabc30670d7a8b684b
- 出典データセット
- uspto-grants-1990_05
- 特許番号
- US04923504
反応ノート
読み込み中…