Potassium cyanate → N-(2,6-difluorophenylsulphonyl)urea
反応式
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[S:9]([NH-:12])(=[O:11])=[O:10].[O-:13][C:14]#[N:15].[K+]>C(O)C>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[S:9]([NH:12][C:14]([NH2:15])=[O:13])(=[O:10])=[O:11]参加物
4
実験手順
2,6-Difluorophenylsulphonylamide in an amount of 9.65 g and 6.5 g of potassium cyanate in 100 ml of ethanol are refluxed for 3 hours. After dilution with water and filtration while hot the solution is acidified with 5 ml of conc. hydrochloric acid. The desired N-(2,6-difluorophenylsulphonyl)urea is obtained in a yield of 10.0 g; melting point 198° C. (decomp.)
後処理
- filtrationAfter dilution with water and filtration while hot the solution
出典と根拠
- ORDレコード
- ord-abf75c66161943cf801083107823cad5
- 出典データセット
- uspto-grants-1990_05
- 特許番号
- US04927452
反応ノート
読み込み中…