2-Imidazoline → 1H-Imidazole, 2-methyl-1-(1-methylethyl)-

HRID 1651293

反応式

HRID 1651293 の反応式
[CH:1]([N:4]1[CH2:8][CH2:7][N:6]=[C:5]1[CH3:9])([CH3:3])[CH3:2].N1CCN=C1>[Cr].[Cu].[Ni]>[CH:1]([N:4]1[CH:8]=[CH:7][N:6]=[C:5]1[CH3:9])([CH3:3])[CH3:2]

参加物

4

反応物 2

HCID 681562-ImidazolineHCID 146929591-Isopropyl-2-methylimidazoline

生成物 1

HCID 146708161H-Imidazole, 2-methyl-1-(1-methylethyl)-収率 98%

試薬・触媒・溶媒 1

HCID 57448902HCID 57448902、化合物触媒

実験手順

A 100-ml three-necked flask equipped with a thermometer, condenser, magnetic stirrer, and nitrogen inlet was charged with 1-isopropyl-2-methylimidazoline (50 g, 0.4 mole) and nickel-copper-chromium catalyst (5.0 g) as described in U.S. Pat. No. 3,152,998. The reaction was carried out at 200° C. with stirring and under a nitrogen atmosphere for about 5 hours. GLC analysis showed that more than 99% of the starting imidazoline had been converted to give the corresponding imidazole with 98.5% selectivity. The product was fractionally distilled under reduced pressure (80° C. at 1.2 mm Hg) to give a clear, colorless liquid in about 98% yield.

後処理

  1. customA 100-ml three-necked flask equipped with a thermometer, condenser, magnetic stirrer, and nitrogen inlet
  2. customwas carried out at 200° C.

出典と根拠

ORDレコード
ord-55532493ab5e4483be8d9bae90864121
出典データセット
uspto-grants-1990_05
特許番号
US04927942

関連ノート

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