Water → HCID 14848514、化合物

HRID 1651776ノート

反応式

HRID 1651776 の反応式
[C:1]([C:5]([Br:8])(Br)[Br:6])([F:4])([F:3])[F:2].[Cl:9][C:10]1[CH:17]=[CH:16][CH:15]=[CH:14][C:11]=1[CH:12]=[O:13].O>CN(C=O)C.[Zn]>[Br:6][C:5]([Br:8])([C:1]([F:4])([F:3])[F:2])[CH:12]([C:11]1[CH:14]=[CH:15][CH:16]=[CH:17][C:10]=1[Cl:9])[OH:13]

参加物

6

反応物 3

HCID 962WaterHCID 69962-ChlorobenzaldehydeHCID 677181,1,1-Tribromo-2,2,2-trifluoroethane

生成物 1

HCID 14848514HCID 14848514、化合物

試薬・触媒・溶媒 2

HCID 23994Zinc触媒HCID 6228Dimethylformamide溶媒

実験手順

83.5 g of CF3CBr3 in anhydrous DMF and 28 g of 2-chlorobenzaldehyde were reacted under a nitrogen atmosphere. The mixture was brought to 5° C. and zinc in powder (g. 16.0) was added to it slowly. Then the mixture was let reach the room temperature and kept under stirring for 6 hours. The mixture was poured into water and extracted three times with ethyl ether.

後処理

  1. customwas brought to 5° C.
  2. customthe room temperature
  3. extractionextracted three times with ethyl ether

出典と根拠

ORDレコード
ord-d6478588fc50402ea4ecf86ec6e72f3e
出典データセット
uspto-grants-1990_05
特許番号
US04929772

反応ノート

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