化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → Hydrochloric Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 2-Chlorobenzimidazole | HCID 78572 | — |
| 反応物 | 3,3-Diphenylpropylamine | HCID 79698 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | Hydrochloric Acid | HCID 313 | — |
| 生成物 | N-(Benzimidazol-2-yl)-3,3-diphenylpropylamine | HCID 11695568 | — |
反応手順
The title compound was prepared from 2-chlorobenzimidazole and 3,3-diphenyl-propylamine by Procedure A. The reaction mixture was added dilute aqueous HCl and CH2Cl2. From the CH2Cl2 phase a precipitate was isolated by filtration yielding the title compound in pure form as its HCl salt (mp 136.5-137.5° C.). MS(ES+) m/z 328 ([M+1]+, 100). 1NMR (DMSO-d6) δ 2.43 (m, 2H), 3.28 (m, 2H), 4.15 (t, 1H), 7.15-7.35 (m, 14H), 9.00 (m, 1H), 12.7 (br s, 1H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07737167B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-00c567a1ba8b42f4a39ab2d6eb23c619 |
| 出典メモ | uspto-grants-2010_06 |