Ammonia → HCID 178511997、化合物

HRID 1654886ノート

反応式

HRID 1654886 の反応式
[Cl:1][C:2]1[CH:25]=[CH:24][C:5]([CH2:6][O:7][C:8]2[C:9]([NH:14][C:15]([NH:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=S)=[N:10][CH:11]=[CH:12][CH:13]=2)=[CH:4][CH:3]=1.[NH3:26]>>[Cl:1][C:2]1[CH:25]=[CH:24][C:5]([CH2:6][O:7][C:8]2[C:9]([NH:14][C:15]([NH:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[NH:26])=[N:10][CH:11]=[CH:12][CH:13]=2)=[CH:4][CH:3]=1

参加物

3

反応物 2

HCID 222AmmoniaHCID 20076930HCID 20076930、化合物

生成物 1

HCID 178511997HCID 178511997、化合物

実験手順

A mixture of N-[3-(4-chlorobenzyloxy)pyrid-2-yl]-N'-phenylthiourea (3.00 g, 0.008 mol), yellow mercuric oxide (2.17g, 0.01 mol) and methanolic ammonia solution (40 ml) was stirred for 48 hours. The solvent was removed in vacuo and the black residue was boiled with chloroform and filtered hot. Evaporation of the solvent and recrystallisation from acetonitrile gave the desired product. Yield 1.8 g (63%), m.p. 173°-174 ° C.

後処理

  1. customThe solvent was removed in vacuo
  2. filtrationfiltered hot
  3. customEvaporation of the solvent and recrystallisation from acetonitrile

出典と根拠

ORDレコード
ord-3845f06657174bff9a63e23c9e062f0e
出典データセット
uspto-grants-1995_04
特許番号
US05409943

反応ノート

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