Water → D-Altrose

HRID 1654977ノート

反応式

HRID 1654977 の反応式
[C@@H:1]12[O:11][CH2:10][C@@H:8]([O:9]1)[C@@H:6]([OH:7])[C@@H:4]([OH:5])[C@@H:2]2[OH:3].[OH2:12]>>[O:12]=[CH:10][C@H:8]([C@@H:6]([C@@H:4]([C@@H:2]([CH2:1][OH:11])[OH:3])[OH:5])[OH:7])[OH:9]

参加物

3

反応物 2

HCID 962WaterHCID 111265751,6-anhydro-beta-D-altropyranose

生成物 1

HCID 94780D-Altrose

反応条件

温度
100 °C

実験手順

0.16 g (1.00 mmol) of the compound (3) was dissolved in 50 ml of water, followed by adding 4.00 g of amberlight IR-120B (proton type cation exchange resin) to the resultant solution. The system thus prepared was kept stirred for 8.5 hours at 100° C. Then, the amberlight IR-120B was removed from the reaction system by means of filtration, followed by washing the cation exchange resin with water. Further, the solvent was removed from the filtrate and the washing water by means of distillation under reduced pressure. Formation of the desired compound of the present invention, i.e., D-altrose (compound 4), was confirmed by thin layer chromatography. It was also confirmed that the raw material compound (3) was mixed with the product compound (4). The mixing ratio of these compounds (3) and (4) was about 1:1.

後処理

  1. customThe system thus prepared
  2. customThen, the amberlight IR-120B was removed from the reaction system by means of filtration
  3. washby washing the cation exchange resin with water
  4. customFurther, the solvent was removed from the filtrate
  5. distillationthe washing water by means of distillation under reduced pressure
  6. additionwas mixed with the product compound (4)

出典と根拠

ORDレコード
ord-023f767936f9433ba63658420882c441
出典データセット
uspto-grants-1995_04
特許番号
US05410038

反応ノート

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