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2-Chlorobenzimidazole → Hydrochloric Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Chlorobenzimidazole | HCID 78572 | — |
| 反応物 | 1-Aminotetralin, (S)- | HCID 7058074 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | Hydrochloric Acid | HCID 313 | — |
| 生成物 | (S)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1H-benzo[d]imidazol-2-amine | HCID 11623093 | — |
反応手順
The title compound was prepared from 2-chlorobenzimidazole and (S)-1,2,3,4-tetrahydro-1-naphthylamine by Procedure A (reflux in toluene for 2 days). The product was purified by preparative LCMS, added HCl and isolated as a HCl salt (white solid, mp 257-258° C.). MS(ES+) m/z 264 ([M+1]+, 100).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07737167B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-e63c02bb260d484daeeb7469e673adba |
| 出典メモ | uspto-grants-2010_06 |