Iodine → Silane, (3-iodopropyl)trimethyl-

HRID 1655990ノート

反応式

HRID 1655990 の反応式
[I:1]I.[Mg:3].[CH3:4][Si:5]([CH3:11])([CH3:10])[CH2:6][CH2:7][CH2:8]O.CS([O-])(=O)=O>CCOCC>[I-:1].[Mg+2:3].[I-:1].[I:1][CH2:8][CH2:7][CH2:6][Si:5]([CH3:11])([CH3:10])[CH3:4]

参加物

7

反応物 4

HCID 807IodineHCID 762131-Propanol, 3-(trimethylsilyl)-HCID 85257MethanesulfonateHCID 5462224Magnesium

生成物 2

HCID 553328Silane, (3-iodopropyl)trimethyl-HCID 5462737Magnesium diiodide

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒2 回

実験手順

An ethereal solution of magnesium iodide was prepared by adding 4.85 g (19 mmol) of iodine to 0.46 g (19 mmol) of magnesium in suspension in 40 ml of dry ether. 28 ml of this solution was added to a solution containing the crude 3-(trimethylsilyl)-1-propanol, methanesulfonate in 10 ml of ether. The reaction mixture was stirred for 3 hours at room temperature and then partitioned between ether and water, the organic phase was separated and further washed with aqueous sodium thiosulfate. After evaporation of the solvent, 1.6 g of (3-iodopropyl)trimethysilane was obtained as a colorless liquid.

後処理

  1. custompartitioned between ether and water
  2. customthe organic phase was separated
  3. washfurther washed with aqueous sodium thiosulfate
  4. customAfter evaporation of the solvent

出典と根拠

ORDレコード
ord-33885d17323f4cb7a2d9119f79b0c513
出典データセット
uspto-grants-1993_10
特許番号
US05252587

反応ノート

読み込み中…