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4-Fluorobenzene-1,2-diamine → N-(5-Fluorobenzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Fluorobenzene-1,2-diamine | HCID 164584 | — |
| 反応物 | 1-Isothiocyanato-1,2,3,4-tetrahydronaphthalene | HCID 21393478 | — |
| 生成物 | N-(5-Fluorobenzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine | HCID 68684304 | — |
反応手順
The title compound was prepared from 4-fluorophenylenediamine and 1-isothiocyanato-1,2,3,4-tetrahydronaphthalene by Procedure D. The title compound was isolated by column chromatography as the free base and as a mixture of enantiomers (solid, mp 220-221° C.). MS(ES+) m/z 282 ([M+1]+, 100).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07737167B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-b9d79720df6a4456b06914d23a4f9fdc |
| 出典メモ | uspto-grants-2010_06 |