2-Butanone, 3-bromo- → HCID 19787526、化合物
反応式
[C:1]([NH:4][C:5]1[CH:6]=[C:7]([CH:9]=[C:10]([CH3:12])[CH:11]=1)[NH2:8])(=[O:3])[CH3:2].Br[CH:14]([CH3:18])[C:15](=O)[CH3:16]>CN(C)C=O>[C:1]([NH:4][C:5]1[CH:6]=[C:7]2[C:9]([C:14]([CH3:18])=[C:15]([CH3:16])[NH:8]2)=[C:10]([CH3:12])[CH:11]=1)(=[O:3])[CH3:2]参加物
4
実験手順
9 g of 3-acetamido-5-methylaniline are dissolved in 20 ml of dimethylformamide and 3.2 ml of 3-bromobutan-2-one are then added. The mixture is left at ambient temperature for 1 hour and the temperature is then raised to 100°-110° C. for one hour. The mixture is cooled and poured into 100 ml of ice-water. The precipitate is drained and washed successively with 50 ml of distilled water, 20 ml of ethanol and 20 ml of isopropyl ether. 4.2 g of white precipitate are obtained.
後処理
- temperaturethe temperature is then raised to 100°-110° C. for one hour
- temperatureThe mixture is cooled
- washwashed successively with 50 ml of distilled water, 20 ml of ethanol and 20 ml of isopropyl ether
出典と根拠
- ORDレコード
- ord-946d25eb59e14301b062b0240541b520
- 出典データセット
- uspto-grants-1993_10
- 特許番号
- US05254135
反応ノート
読み込み中…