Sulfuric Acid → 1,1,3,3-Tetrafluoro-2-methylpropan-2-ol

HRID 1656841ノート

反応式

HRID 1656841 の反応式
[CH3:1][C:2]([CH:6]([F:8])[F:7])=[C:3]([F:5])[F:4].S(=O)(=O)(O)[OH:10]>O>[CH3:1][C:2]([OH:10])([CH:6]([F:8])[F:7])[CH:3]([F:5])[F:4]

参加物

4

反応物 2

HCID 1118Sulfuric AcidHCID 232333371,1,3,3-Tetrafluoro-2-methyl-1-propene

生成物 1

HCID 2383921,1,3,3-Tetrafluoro-2-methylpropan-2-ol

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

As another example, 2-methyl-1,1,3,3-tetrafluoro-2-propanol may be prepared by fluorinating commercially available 1,1-dichloro-2-propanone to form 1,1-difluoro-2-propanone which may then be reacted with CF2 carbene to form 2-methyl-1,1,3,3-tetrafluoro-1-propene. The 2-methyl-1,1,3,3-tetrafluoro-1-propene may then be reacted with sulfuric acid and then water to form 2-methyl-1,1,3,3-tetrafluoro-2-propanol.

出典と根拠

ORDレコード
ord-53b1db575a3d42f9bcfb340c59adbaf6
出典データセット
uspto-grants-1993_10
特許番号
US05254755

反応ノート

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