関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Dimethylphenylsilane | HCID 13014 | — |
| 反応物 | 1-Cyano-2-methyl-3-prop-2-enylbenzene | HCID 19786485 | — |
| 触媒 | Platinate(2-), hexachloro-, hydrogen, hydrate (1:2:1), (OC-6-11)- | HCID 16211507 | — |
| 溶媒 | Isopropanol | HCID 3776 | — |
| 溶媒 | Cyclohexane | HCID 8078 | — |
| 生成物 | Dimethyl-3-(2'-methyl-3'-cyanophenyl)-propylphenylsilane | HCID 19786496 | 73.1% |
反応手順
9.0 g of 1-cyano-2-methyl-3-prop-2-enylbenzene are dissolved in 100 ml of absolute cyclohexane, and 7.75 g of dimethylphenylsilane are added at room temperature. 0.1 g of hexachloroplatinic acid hexahydrate, dissolved in 2 ml of absolute isopropanol, is added to this mixture. The reaction mixture is stirred for 3 hours at 55° C. The solvent is removed by distillation in a rotary evaporator. High boiling components are separated off by distillation under reduced pressure (condensate 82°-105° C./0.1 mbar). The residue is purified by column chromatography (silica gel/toluene). 12.2 g of dimethyl-3-(2'-methyl-3'-cyanophenyl)-propylphenylsilane are obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05256666 |
|---|
| 出典データセット | uspto-grants-1993_10 |
|---|
| ORD ID | ord-8e79860bd1564b1ebdde728909d9ad0d |
|---|
| 出典メモ | uspto-grants-1993_10 |
|---|
