Sulfuric Acid → HCID 21531595、化合物

反応式

[Br:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[CH:5]=[CH:4][C:3]=1[C:11]([CH3:14])([CH3:13])[CH3:12].[Cl:15][CH2:16]OC.S(=O)(=O)(O)O>>[Br:1][C:2]1[C:3]([C:11]([CH3:14])([CH3:13])[CH3:12])=[C:4]([CH:5]=[C:6]([N+:8]([O-:10])=[O:9])[CH:7]=1)[CH2:16][Cl:15]

参加物

反応物 3

HCID 1118Sulfuric Acid

HCID 7864Chloromethyl Methyl Ether

HCID 2385872-Bromo-1-tert-butyl-4-nitrobenzene

生成物 1

HCID 21531595HCID 21531595、化合物

実験手順

A mixture of 30 parts of 2-bromo-1-tert-butyl-4-nitrobenzene and 30 parts of chloromethylmethyl ether is stirred vigorously while adding dropwise 20 parts of 60% fuming sulfuric acid. The resultant mixture is allowed to stand until the apparent reaction ceases and is then poured into ice water. The solid is removed by filtration and washed with water to give 3-bromo-2-tert-butyl-5-nitrobenzyl chloride.