Quinoline → 2-Nonen-1-ol, (2Z)-
反応式
[CH2:1]([OH:10])[C:2]#[C:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9].N1C2C(=CC=CC=2)C=CC=1>CO.[Pd].CC([O-])=O.CC([O-])=O.[Pb+2]>[CH2:1]([OH:10])/[CH:2]=[CH:3]\[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9]参加物
5
実験手順
2-Nonyn- 1-ol (20 g, 0.4 mole) in 200 ml methyl alcohol is hydrogenated in a Parr bomb using a Lindlar catalyst (0.5 g Pd/BaSO4) and quinoline (0.5 g). The hydrogenation was monitored by gas liquid partition chromatography on diethylene glycol succinate. Hydrogenation is stopped when the concentration of the acetylenic alcohol equals that of the saturated alcohol. The hydrogenation mixture is filtered, diluted with water and extracted with ether. The ether extract is dried over anhydrous sodium sulfate, concentrated and distilled to yield 13 g of cis-2-nonen-1-ol, b.p. 60°-64°C/0.5 mm.
後処理
- custompartition chromatography on diethylene glycol succinate
- filtrationThe hydrogenation mixture is filtered
- additiondiluted with water
- extractionextracted with ether
- extractionThe ether extract
- dry with materialis dried over anhydrous sodium sulfate
- concentrationconcentrated
- distillationdistilled
出典と根拠
- ORDレコード
- ord-a0faf13214f74682a1fc1f67ec67e44f
- 出典データセット
- uspto-grants-1976_06
- 特許番号
- US03962321
反応ノート
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