Hydrochloric Acid → HCID 12223719、化合物
反応式
C([O:4][CH:5]([CH2:30][O:31]C(=O)C)[CH2:6][N:7]1[C:27](=[O:28])[C:11]2[CH:12]=[CH:13][CH:14]=[C:15]3[S:16][C:17]4[CH:18]=[CH:19][C:20]([C:23]([F:26])([F:25])[F:24])=[CH:21][C:22]=4[N:9]([C:10]=23)[C:8]1=[O:29])(=O)C.Cl>CO>[OH:4][CH:5]([CH2:30][OH:31])[CH2:6][N:7]1[C:27](=[O:28])[C:11]2[CH:12]=[CH:13][CH:14]=[C:15]3[S:16][C:17]4[CH:18]=[CH:19][C:20]([C:23]([F:24])([F:25])[F:26])=[CH:21][C:22]=4[N:9]([C:10]=23)[C:8]1=[O:29]参加物
4
実験手順
A mixture of 48.1 g. (0.0975 mol.) of 2-(2,3-diacetoxypropyl)-10-trifluoromethyl-1H-pyrimido[5,4,3-kl]phenothiazine-1,3(2H)-dione in 200 ml. of methanol and 25 ml. of concentrated hydrochloric acid was heated under reflux for 0.5 hour, then allowed to stand overnight at ambient temperature. The white solid that precipitated was isolated by filtration and washed with water to give the title compound, m.p. 159°-162° (chloroform).
後処理
- addition