Acetic Acid → HCID 54734744、化合物
反応式
[Cl:1][C:2]1[CH:10]=[C:6]([C:7](O)=[O:8])[C:5]([NH:11][CH2:12][CH3:13])=[CH:4][CH:3]=1.[C:14]([OH:17])(=O)[CH3:15]>C(OC(=O)C)(=O)C>[Cl:1][C:2]1[CH:10]=[C:6]2[C:5](=[CH:4][CH:3]=1)[N:11]([CH2:12][CH3:13])[C:14](=[O:17])[CH:15]=[C:7]2[OH:8]参加物
4
実験手順
5-Chloro-N-ethyl anthranilic acid (13.1g; 0.006 mole) in acetic acid (35 ml) and acetic anhydride (35 ml) was refluxed for 24 hours. The cooled mixture was poured into ice-water and basified to pH 14. The precipitated red oil was separated and the supernatant acidified to pH 5 to give the title compound as a white crystalline solid. m.p. (EtOH) 305°-8°C (Found C, 58.80; H, 4.64; N, 6.49; Cl, 15.95; C11H10CINO2 requires; C, 59.07; H, 4.51; N, 6.26; Cl, 15.85%).
後処理
- customThe precipitated red oil was separated
出典と根拠
- ORDレコード
- ord-fb3b90041a4f453e859f3179c74d5d1b
- 出典データセット
- uspto-grants-1976_06
- 特許番号
- US03962445
反応ノート
読み込み中…