Heptafluorobutyryl Chloride → 5-(Trifluoromethyl)-3-nitro-2-(2,2,3,3,4,4,4-heptafluorobutyramido)pyridine

HRID 1658361

反応式

HRID 1658361 の反応式
[F:1][C:2]([F:14])([F:13])[C:3]1[CH:4]=[C:5]([N+:10]([O-:12])=[O:11])[C:6]([NH2:9])=[N:7][CH:8]=1.[F:15][C:16]([F:27])([C:20]([F:26])([F:25])[C:21]([F:24])([F:23])[F:22])[C:17](Cl)=[O:18]>>[F:14][C:2]([F:1])([F:13])[C:3]1[CH:4]=[C:5]([N+:10]([O-:12])=[O:11])[C:6]([NH:9][C:17](=[O:18])[C:16]([F:15])([F:27])[C:20]([F:25])([F:26])[C:21]([F:24])([F:23])[F:22])=[N:7][CH:8]=1

参加物

3

反応物 2

HCID 67810Heptafluorobutyryl ChlorideHCID 106083913-Nitro-5-(trifluoromethyl)pyridin-2-amine

生成物 1

HCID 203554885-(Trifluoromethyl)-3-nitro-2-(2,2,3,3,4,4,4-heptafluorobutyramido)pyridine

実験手順

5-(Trifluoromethyl)-3-nitro-2-aminopyridine is reacted with perfluorobutyryl chloride to yield 5-(trifluoromethyl)-3-nitro-2-(2,2,3,3,4,4,4,-heptafluorobutyramido)pyridine, which when hydrogenated yields 6-(trifluoromethyl)-1-hydroxy-2-(perfluoro-n-propyl)-1H-imidazo(4,5-b)pyridine.

出典と根拠

ORDレコード
ord-1d6888d8da3a44aea7788a02d1d6b6a0
出典データセット
uspto-grants-1976_06
特許番号
US03963734

関連ノート

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