Methanol → Methyl 7-methyl-9H-xanthene-2-carboxylate

HRID 1658412ノート

反応式

HRID 1658412 の反応式
[CH3:1][C:2]1[CH:15]=[C:14]2[C:5]([O:6][C:7]3[CH:8]=[CH:9][C:10]([C:16]([OH:18])=[O:17])=[CH:11][C:12]=3[CH2:13]2)=[CH:4][CH:3]=1.[CH3:19]O.S(=O)(=O)(O)O>O>[CH3:1][C:2]1[CH:15]=[C:14]2[C:5]([O:6][C:7]3[CH:8]=[CH:9][C:10]([C:16]([O:18][CH3:19])=[O:17])=[CH:11][C:12]=3[CH2:13]2)=[CH:4][CH:3]=1

参加物

5

反応物 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 215006717-Methyl-9H-xanthene-2-carboxylic acid

生成物 1

HCID 21500836Methyl 7-methyl-9H-xanthene-2-carboxylate

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
40 °C

実験手順

Twenty-six grams of 7-methylxanthene-2-carboxylic acid is added to 400 ml. of absolute methanol. To the resultant solution are added 18 ml. of concentrated sulfuric acid and the mixture is then heated at reflux for about 2 hours. The mixture is then cooled to 40°C and sufficient water is added to bring the total volume to 1400 ml. The resultant mixture is then filtered to give methyl 7-methylxanthene-2-carboxylate.

後処理

  1. temperatureat reflux for about 2 hours
  2. filtrationThe resultant mixture is then filtered

出典と根拠

ORDレコード
ord-60753139020341db80140cf8cd537def
出典データセット
uspto-grants-1976_06
特許番号
US03963752

反応ノート

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