2-Butene, 1,4-dibromo- → HCID 54196002、化合物

HRID 1658435ノート

反応式

HRID 1658435 の反応式
[Br:1][CH2:2][CH:3]=[CH:4][CH2:5]Br.[C:7]([O-:10])(=[O:9])[CH3:8].[Na+]>CN(C)C=O>[C:7]([O:10][CH2:5][CH:4]=[CH:3][CH2:2][Br:1])(=[O:9])[CH3:8]

参加物

4

反応物 2

HCID 131802-Butene, 1,4-dibromo-HCID 517045Sodium Acetate

生成物 1

HCID 54196002HCID 54196002、化合物

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

反応条件

温度
100 °C

実験手順

93 g of 1,4-dibromobut-2-ene are treated in 250 ml of dimethylformamide with 35.5 g of anhydrous sodium acetate and stirred for 1 hour at 100°C. The mixture is extensively freed from dimethylformamide on a rotary evaporator and the residue is partitioned between water and methylene chloride. The methylene chloride phase is dried over calcium chloride, filtered and concentrated. The residue is distilled under a water-jet vacuum, whereby the fractions are collected between 95° and 105°C at 10-15 mm; nD25 =1.502. There is obtained 1-acetoxy-4-bromobut-2-ene as a colourless liquid.

後処理

  1. customThe mixture is extensively freed from dimethylformamide on a rotary evaporator
  2. customthe residue is partitioned between water and methylene chloride
  3. dry with materialThe methylene chloride phase is dried over calcium chloride
  4. filtrationfiltered
  5. concentrationconcentrated
  6. distillationThe residue is distilled under a water-jet vacuum, whereby the fractions
  7. customare collected between 95° and 105°C at 10-15 mm

出典と根拠

ORDレコード
ord-8ff3adfdd76a44619c366bf142486e45
出典データセット
uspto-grants-1976_06
特許番号
US03963777

反応ノート

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