2-Thiazolidinone,4-thioxo- → HCID 178508330、化合物

HRID 1658821

反応式

HRID 1658821 の反応式
[O:1]=[C:2]1[NH:6][C:5](=[S:7])[CH2:4][S:3]1.[NH:8]=[C:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11](=N)[NH:10]1>CO>[NH:8]=[C:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11](=[C:4]2[S:3][C:2](=[O:1])[NH:6][C:5]2=[S:7])[NH:10]1

参加物

4

反応物 2

HCID 15395952-Thiazolidinone,4-thioxo-HCID 178508669HCID 178508669、化合物

生成物 1

HCID 178508330HCID 178508330、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

To a stirred solution of 49.7 parts of 2-oxo-4-thioxothiazolidine in 990 parts of methanol there was added at 40°C and under an atmosphere of nitrogen 54.3 parts of powdered 1,3-diiminoisoindoline. Initially, a thick slurry resulted. The reaction mixture was stirred at room temperature for 2 hours during which time the mixture gradually thinned. The mixture was then heated at reflux for approximately two hours and after cooling to 25°C, was filtered. The collected solid was washed with fresh methanol and dried in vacuo at 50°C to obtain 1-imino-3-(2-oxo-4-thioxo-5-thiazolidinylidene)isoindoline as an orange powder melting at 267°-8°C (dec.).

後処理

  1. customInitially, a thick slurry resulted
  2. temperatureThe mixture was then heated
  3. temperatureat reflux for approximately two hours
  4. temperatureafter cooling to 25°C
  5. filtrationwas filtered
  6. washThe collected solid was washed with fresh methanol
  7. customdried in vacuo at 50°C

出典と根拠

ORDレコード
ord-4888a38e17f749eda125d66650a5a540
出典データセット
uspto-grants-1976_06
特許番号
US03966753

関連ノート

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