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1-(1-Piperidinylcarbonyl)piperazine → 4-(4-Piperidinocarbonyl-1-piperazinyl)-6,7-dimethoxyquinazoline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(1-Piperidinylcarbonyl)piperazine | HCID 1095015 | — |
| 反応物 | 4-Chloro-6,7-dimethoxyquinazoline | HCID 2769364 | — |
| 生成物 | 4-(4-Piperidinocarbonyl-1-piperazinyl)-6,7-dimethoxyquinazoline | HCID 21527121 | — |
反応手順
In like manner, 1-chloro-6,7-diethoxyisoquinoline and 1-(piperidinocarbonyl)piperazine react to afford 1-(4-piperidinocarbonyl-1-piperazinyl)-6,7-diethoxyisoquinoline, while 4-chloro-6,7-dimethoxyquinazoline and 1-(piperidinocarbonyl)piperazine react to afford 4-(4-piperidinocarbonyl-1-piperazinyl)-6,7-dimethoxyquinazoline respectively. The latter compound is, of course, identical in every respect with the product of Example V.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03966936 |
| 出典データセット | uspto-grants-1976_06 |
| ORD ID | ord-8a20e72eb138456abaccf1ead34f882f |
| 出典メモ | uspto-grants-1976_06 |