Ethyl 6-(4-chlorophenyl)-2,4,6-trioxohexanoate → Ethyl 6-(4-chlorophenyl)-4-oxo-4H-pyran-2-carboxylate
反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:20])[CH2:9][C:10](=[O:19])[CH2:11][C:12](=O)[C:13]([O:15][CH2:16][CH3:17])=[O:14])=[CH:4][CH:3]=1>S(=O)(=O)(O)O>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[O:20][C:12]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[CH:11][C:10](=[O:19])[CH:9]=2)=[CH:6][CH:7]=1参加物
3
実験手順
A solution of ethyl 6-(4-chlorophenyl)-2,4,6-trioxohexanoate (0.26 g) in cold concentrated sulphuric acid (3 ml) was stirred for 3 hours at 0°-5° C. then poured on to ice (10 g). The solid product was recrystallised from ethanol-water to give the title product identical (mp, IR and NMR, and thin-layer chromatography) with the product described in Example 12.
後処理
- customThe solid product was recrystallised from ethanol-water
出典と根拠
- ORDレコード
- ord-f0d4e2e35eee4efba0e8b7e7144102bd
- 出典データセット
- uspto-grants-1981_12
- 特許番号
- US04304728
反応ノート
読み込み中…