Ethyl 6-(4-chlorophenyl)-2,4,6-trioxohexanoate → 6-(4-Chlorophenyl)-4-oxo-4H-pyran-2-carboxylic acid
反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:20])[CH2:9][C:10](=[O:19])[CH2:11][C:12](=O)[C:13]([O:15]CC)=[O:14])=[CH:4][CH:3]=1>O1CCOCC1.Cl>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[O:20][C:12]([C:13]([OH:15])=[O:14])=[CH:11][C:10](=[O:19])[CH:9]=2)=[CH:6][CH:7]=1参加物
4
実験手順
A solution of ethyl 6-(4-chlorophenyl)-2,4,6-trioxohexanoate (0.30 g) in dioxan (2 ml) and concentrated hydrochloric acid (2 ml) was heated on a steam bath for 2 hours. The pale solid which formed was recrystallised from ethanol to give the title product identical (mp, IR and NMR, and thin-layer chromatography) with the product described in Example 24.
後処理
- customThe pale solid which formed
- customwas recrystallised from ethanol
出典と根拠
- ORDレコード
- ord-008400f3f200463c9c5407b4c91256c6
- 出典データセット
- uspto-grants-1981_12
- 特許番号
- US04304728
反応ノート
読み込み中…