Formamide → 4-chloroisoindole-1,3-dione
反応式
[Cl:1][C:2]1[CH:12]=[CH:11][CH:10]=[C:4]2[C:5]([O:7][C:8](=O)[C:3]=12)=[O:6].C([NH2:15])=O>O>[Cl:1][C:2]1[CH:12]=[CH:11][CH:10]=[C:4]2[C:5]([NH:15][C:8](=[O:7])[C:3]=12)=[O:6]参加物
4
反応条件
- 温度
- 100 °C
実験手順
(b 1) 300 parts of 3-chlorophthalic anhydride in 1,200 parts by volume of formamide are stirred for 2 hours at 140° C. The mixture is then allowed to cool to 100° C. after which the solution is poured into 5,000 parts by volume of water. The precipitate which forms is filtered off, washed with water and dried under reduced pressure. 275 parts (92.2% of theory) of 3-chlorophthalimide, of melting point 236°-238° C., are obtained.
後処理
- filtrationThe precipitate which forms is filtered off
- washwashed with water
- customdried under reduced pressure
出典と根拠
- ORDレコード
- ord-13844a440a624164881cb39fa99eb1bf
- 出典データセット
- uspto-grants-1981_12
- 特許番号
- US04306074
反応ノート
読み込み中…