化工社化工社 化学情報印刷レポート · 研究参考用
1,2,4,5-Tetrachlorobenzene → 2,3,4-Trichlorophenol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,2,4,5-Tetrachlorobenzene | HCID 7270 | — |
| 反応物 | Benzene, (trichloromethoxy)- | HCID 40773 | — |
| 反応物 | Aluminum(III) Chloride | HCID 6451240 | — |
| 溶媒 | O-Xylene | HCID 7237 | — |
| 生成物 | 2,3,4-Trichlorophenol | HCID 27582 | 97% |
反応手順
A mixture of trichloroanisole (0.1 g mol; 21.15 g) and 1,2,4,5-tetrachlorobenzene (10 g) in xylene (80 ml) was heated at 80° C. with aluminium trichloride (0.05 mole; 6.65 g) for five hours. Trichlorophenol was isolated in 97% yield (based on trichloroanisole) as described in Example I below. Unchanged tetrachlorobenzene, together with xylene self condensation product (total 13.25 g) was isolated from the neutral product fraction after solvent removal.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04306098 |
| 出典データセット | uspto-grants-1981_12 |
| ORD ID | ord-c9c1696fd2094c909c2e138e64c092ea |
| 出典メモ | uspto-grants-1981_12 |