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Thionyl Chloride → 7-Ethylsulfonyl-1,4-benzodioxane-5-carbonyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 7-Ethylsulfonyl-1,4-benzodioxane-5-carboxylic acid | HCID 20544758 | — |
| 触媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 7-Ethylsulfonyl-1,4-benzodioxane-5-carbonyl chloride | HCID 20544728 | 100% |
反応手順
243 g of thionyl chloride, a few drops of dimethyl formamide and 139 g of 7-ethylsulfonyl-1,4-benzodioxane-5-carboxylic acid were introduced into a balloon flask provided with a condenser. The mixture was heated and then the thionyl chloride in excess was distilled off under vacuum. 148 g of 7-ethylsulfonyl-1,4-benzodioxane-5-carbonyl chloride were obtained (M.P.: 146°-147° C.; yield: 100%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04306072 |
| 出典データセット | uspto-grants-1981_12 |
| ORD ID | ord-f7544609b77d47638bd233d31bc2ba4d |
| 出典メモ | uspto-grants-1981_12 |