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HRID 1660332作成日:2026年10月27日

N-[(7-methoxy-1,3,4,9-tetrahydro-1-methylpyrano-[3,4-b]indol-1-yl)methyl]-acetamide → 1-(Acetamidomethyl)-1-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indole

https://huagongshe.com/reaction/1660332

反応式

関与物質

役割名称HCID仕込み量
反応物N-[(7-methoxy-1,3,4,9-tetrahydro-1-methylpyrano-[3,4-b]indol-1-yl)methyl]-acetamideHCID 20485044—
反応物N-[(8-ethyl-1,3,4,9-tetrahydro-1-methylpyrano[3,4-b]indol-1-yl)methyl]-acetamideHCID 20485069—
反応物N-[(6-phenylmethoxy-1,3,4,9-tetrahydro-1-methylpyrano[3,4-b]indol-1-yl)methyl]-acetamideHCID 20485103—
生成物1-(Acetamidomethyl)-1-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indoleHCID 12708180—

反応手順

In the same manner but replacing indole-3-ethanol with an equivalent amount of 7-ethylindole-3-ethanol, 6-methoxyindole-3-ethanol or 5-phenylmethoxy-indole-3-ethanol, the following compounds of formula 11a are obtained, respectively: N-[(8-ethyl-1,3,4,9-tetrahydro-1-methylpyrano[3,4-b]indol-1-yl)methyl]-acetamide, N-[(7-methoxy-1,3,4,9-tetrahydro-1methylpyrano-[3,4-b]indol-1-yl)methyl]-acetamide and N-[(6-phenylmethoxy-1,3,4,9-tetrahydro-1-methylpyrano[3,4-b]indol-1-yl)methyl]-acetamide.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US04307234
出典データセットuspto-grants-1981_12
ORD IDord-8cb6ae96872f4856b190496885dc9e0a
出典メモuspto-grants-1981_12