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Benzene, 1-chloro-4-fluoro- → 1-(4-Chlorophenyl)-2-ethyl-1'-methylspiro[indoline-3,4'-piperidine]
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzene, 1-chloro-4-fluoro- | HCID 9604 | — |
| 反応物 | 2-Ethyl-1'-methylspiro[indoline-3,4'-piperidine] | HCID 12801643 | — |
| 生成物 | 1-(4-Chlorophenyl)-2-ethyl-1'-methylspiro[indoline-3,4'-piperidine] | HCID 20442637 | — |
反応手順
By following the procedure of Example 1c, 2-ethyl-1'-methylspiro[indoline-3,4'-piperidine], the free base of part a, is treated with 4-chlorofluorobenzene to yield 1-(4-chlorophenyl)-2-ethyl-1'-methylspiro[indoline-3,4'-piperidine].
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04307235 |
| 出典データセット | uspto-grants-1981_12 |
| ORD ID | ord-a7440c80a1bb447e89e390fa84d7d920 |
| 出典メモ | uspto-grants-1981_12 |