Ammonia → 2-[(aminocarbamothioyl)amino]acetamide
反応式
C([O:3][C:4]([CH2:6][NH:7][C:8](=[S:11])[NH:9][NH2:10])=O)C.[NH3:12]>C(O)C>[C:4]([CH2:6][NH:7][C:8](=[S:11])[NH:9][NH2:10])(=[O:3])[NH2:12]参加物
4
反応条件
- 温度
- 25 °C
実験手順
4-Ethoxycarbonylmethyl-thiosemicarbazide (8.33 g) (GANTE and LANTSCH, Chem. Ber., 97, 989 (1964) are suspended in a saturated solution (250 cc) of ammonia in ethanol, and the reaction mixture is stirred at 25° C. for 22 hours. The insoluble matter is filtered off and washed with alcohol (2×25 cc) and ether (2×50 cc); after drying, 4-carbamylmethyl-thiosemicarbazide (6.2 g), m.p.=188° C., is obtained.
後処理
- filtrationThe insoluble matter is filtered off
- washwashed with alcohol (2×25 cc) and ether (2×50 cc)
- customafter drying
出典と根拠
- ORDレコード
- ord-eb2f732fa1e44721a1127b28cfc1c5f1
- 出典データセット
- uspto-grants-1981_12
- 特許番号
- US04307233
反応ノート
読み込み中…