関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Oleic Acid | HCID 445639 | — |
| 反応物 | HCID 178460681 | HCID 178460681 | — |
| 触媒 | Di-tert-amyl peroxide | HCID 25320 | — |
| 生成物 | 10-[Hydroxy-(2,4,4-trimethyl-pentyl)-phosphinoyl]-octadecanoic acid | HCID 57909108 | 83% |
反応手順
6.31 g (0.0354 moles) of 2,4,4-trimethylpentyl phosphinic acid, 10 g (0.0354 moles) of oleic acid and 0.25 mL (0.0012 moles) of di-tert-amylperoxide are mixed in a 50 mL single neck flask. The mixture is purged with argon to remove oxygen and is heated under argon for 6 hours at 140° C. Tert-amyl alcohol is removed by distillation and 13.5 g (83% yield) of 10-[hydroxy-(2,4,4-trimethyl-pentyl)-phosphinoyl]-octadecanoic acid is obtained as a viscous oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08030435B2 |
|---|
| 出典データセット | uspto-grants-2011_10 |
|---|
| ORD ID | ord-64f25c68bad34c9fb8f35b3f7ff2a61a |
|---|
| 出典メモ | uspto-grants-2011_10 |
|---|
