Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) → Methyl 4-hydroxy-3-(2-methylprop-1-en-1-yl)benzoate
反応式
[CH3:1][C:2]([CH3:21])=[CH:3][C:4]1[CH:5]=[C:6]([CH:11]=[CH:12][C:13]=1[O:14]C1CCCCO1)[C:7]([O:9][CH3:10])=[O:8].CC1C=CC(S([O-])(=O)=O)=CC=1.C1C=C[NH+]=CC=1>CO>[OH:14][C:13]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][C:4]=1[CH:3]=[C:2]([CH3:21])[CH3:1]参加物
4
実験手順
To a stirred mixture of 66.20A (0.460 g, 2 mmol) in MeOH (8 mL) was added PPTS (0.04 g, 0.2 mmol). The reaction mixture was then stirred for 24 hours and then concentrated in vacuo. The residue was purified on silica gel (0-20% EtOAc in hexanes) to yield 66.20B as a colorless oil (0.320 g, 98% yield).
後処理
- concentrationconcentrated in vacuo
- customThe residue was purified on silica gel (0-20% EtOAc in hexanes)
出典と根拠
- ORDレコード
- ord-66505642181142728716234bf9ff229e
- 出典データセット
- uspto-grants-2011_10
- 特許番号
- US08030354B2
反応ノート
読み込み中…