1-Bromo-2,4-dimethoxybenzene → 3-(2,4-dimethoxyphenyl)-3-hydroxy-5,6-dimethoxy-1,3-dihydro-2H-indol-2-one

HRID 1662615

反応式

HRID 1662615 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][C:11]=1[O:12][CH3:13])[NH:8][C:7](=[O:14])[C:6]2=[O:15].[CH3:16][O:17][C:18]1[CH:23]=[C:22]([O:24][CH3:25])[CH:21]=[CH:20][C:19]=1Br>>[CH3:16][O:17][C:18]1[CH:23]=[C:22]([O:24][CH3:25])[CH:21]=[CH:20][C:19]=1[C:6]1([OH:15])[C:5]2[C:9](=[CH:10][C:11]([O:12][CH3:13])=[C:3]([O:2][CH3:1])[CH:4]=2)[NH:8][C:7]1=[O:14]

参加物

3

反応物 2

HCID 872661-Bromo-2,4-dimethoxybenzeneHCID 47391485,6-dimethoxy-2,3-dihydro-1H-indole-2,3-dione

生成物 1

HCID 231206493-(2,4-dimethoxyphenyl)-3-hydroxy-5,6-dimethoxy-1,3-dihydro-2H-indol-2-one収率 59.6%

実験手順

With 1.38 g of 5,6-dimethoxyisatin and 3.61 g of 2,4-dimethoxy bromobenzene as starting material, 1.37 g of the title compound (brown solid) was obtained by a similar method to Step 21-1.

出典と根拠

ORDレコード
ord-cecef418db5544b49e5b930eceee4b6d
出典データセット
uspto-grants-2011_10
特許番号
US08030499B2

関連ノート

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