Hydrochloric Acid → (4R)-1-(5-chloro-3-[2-methoxy-5-(2-piperazin-1-ylethyl)phenyl]-1-{[4-methoxy-2-(trifluoromethoxy)phenyl]sulfonyl}-2-oxo-2,3-dihydro-1H-indol-3-yl)-4-hydroxy-N,N-dimethyl-L-prolinamide

反応式

Cl.[Cl:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[N:8]([S:12]([C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][C:16]=1[O:23][C:24]([F:27])([F:26])[F:25])(=[O:14])=[O:13])[C:7](=[O:28])[C:6]2([C:40]1[CH:41]=[C:42]([CH2:48][CH2:49][N:50]2[CH2:55][CH2:54][N:53](C(OC(C)(C)C)=O)[CH2:52][CH2:51]2)[CH:43]=[CH:44][C:45]=1[O:46][CH3:47])[N:29]1[CH2:33][C@H:32]([OH:34])[CH2:31][C@H:30]1[C:35]([N:37]([CH3:39])[CH3:38])=[O:36].C([O-])(O)=O.[Na+]>CCOC(C)=O>[Cl:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[N:8]([S:12]([C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][C:16]=1[O:23][C:24]([F:25])([F:27])[F:26])(=[O:13])=[O:14])[C:7](=[O:28])[C:6]2([N:29]1[CH2:33][C@H:32]([OH:34])[CH2:31][C@H:30]1[C:35]([N:37]([CH3:38])[CH3:39])=[O:36])[C:40]1[CH:41]=[C:42]([CH2:48][CH2:49][N:50]2[CH2:51][CH2:52][NH:53][CH2:54][CH2:55]2)[CH:43]=[CH:44][C:45]=1[O:46][CH3:47]