N-Hydroxyphthalimide → O-(2,6-Dichloro-pyridin-4-ylmethyl)-hydroxylamine hydrochloride

HRID 1663113ノート

反応式

HRID 1663113 の反応式
[OH:1][N:2]1C(=O)C2=CC=CC=C2C1=O.Br[CH2:14][C:15]1[CH:20]=[C:19]([Cl:21])[N:18]=[C:17]([Cl:22])[CH:16]=1>>[ClH:21].[Cl:21][C:19]1[CH:20]=[C:15]([CH2:14][O:1][NH2:2])[CH:16]=[C:17]([Cl:22])[N:18]=1

参加物

3

反応物 2

HCID 10665N-HydroxyphthalimideHCID 27818294-(Bromomethyl)-2,6-dichloropyridine

生成物 1

HCID 86615646O-(2,6-Dichloro-pyridin-4-ylmethyl)-hydroxylamine hydrochloride

実験手順

Prepared by a similar procedure as described for preparation 18. Starting materials: N-hydroxyphthalimide and 4-bromomethyl-2,6-dichloropyridin (Maybridge). 1H-NMR (DMSO-d6) δ 11.2 (br, 3H), 7.62 (s, 2H), 5.18 (s, 2H).

後処理

  1. customPrepared by a similar procedure
  2. customas described for preparation 18

出典と根拠

ORDレコード
ord-ed5e4705eefd45daba55b4a84794e02a
出典データセット
uspto-grants-2011_10
特許番号
US08034811B2

反応ノート

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