N-Hydroxyphthalimide → O-[(1,3-Thiazol-4-yl)methyl]hydroxylamine--hydrogen chloride (1/1)

反応式

[OH:1][N:2]1C(=O)C2=CC=CC=C2C1=O.Cl.[Cl:14][CH2:15][C:16]1[N:17]=[CH:18][S:19][CH:20]=1>>[ClH:14].[S:19]1[CH:20]=[C:16]([CH2:15][O:1][NH2:2])[N:17]=[CH:18]1

参加物

反応物 2

HCID 10665N-Hydroxyphthalimide

HCID 27632894-(Chloromethyl)-1,3-thiazole hydrochloride

生成物 1

HCID 54604191O-[(1,3-Thiazol-4-yl)methyl]hydroxylamine--hydrogen chloride (1/1)

実験手順

Prepared by a similar procedure as described for preparation 18. Starting materials: N-hydroxyphthalimide and 4-(chloromethyl)thiazole hydrochloride (TCl). 13C-NMR (DMSO-d6) δ 155.1, 149.2, 121.4, 70.3.

後処理

customPrepared by a similar procedure
customas described for preparation 18

出典と根拠

ORDレコード: ord-58b55d0b54fb4618998d0116035e8ca7
出典データセット: uspto-grants-2011_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08034811B2

反応ノート

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