N-Hydroxyphthalimide → O-(2-Phenyl-thiazol-4-ylmethyl)-hydroxylamine hydrochloride

反応式

[OH:1][N:2]1C(=O)C2=CC=CC=C2C1=O.Cl.[Cl:14][CH2:15][C:16]1[N:17]=[C:18]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[S:19][CH:20]=1>>[ClH:14].[C:21]1([C:18]2[S:19][CH:20]=[C:16]([CH2:15][O:1][NH2:2])[N:17]=2)[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

参加物

反応物 2

HCID 10665N-Hydroxyphthalimide

HCID 162436754-(Chloromethyl)-2-phenyl-1,3-thiazole hydrochloride

生成物 1

HCID 67132053O-(2-Phenyl-thiazol-4-ylmethyl)-hydroxylamine hydrochloride

実験手順

Prepared by a similar procedure as described for preparation 12, starting from N-hydroxyphthalimide and 4-chloromethyl-2-phenyl-thiazole hydrochloride.

後処理

customPrepared by a similar procedure
customas described for preparation 12

出典と根拠

ORDレコード: ord-6c9394c052064796ae2ac6cf37d9e15f
出典データセット: uspto-grants-2011_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08034811B2

反応ノート

読み込み中…