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Water → 4,4'-[(2-Oxoimidazolin-1,3-diyl)bis(methylene)]-bis(benzonitrile)
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | 2-Imidazolidinone | HCID 8453 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | 4-(Bromomethyl)benzonitrile | HCID 86996 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 4,4'-[(2-Oxoimidazolin-1,3-diyl)bis(methylene)]-bis(benzonitrile) | HCID 70091659 | — |
反応手順
To sodium hydride (2.4 g, 60 mmol) in dimethylformamide (50 mL) at 0° C. was added imidazolin-2-one (2.6 g, 30 mmol). After stirring for 20 minutes 4-(bromomethyl)benzonitrile (13 g, 66 mmol) was added and the mixture was warmed to ambient temperature. After stirring for 1 hour the reaction was poured into water and a solid formed. The solid was filtered to give 4,4'-[(2-oxoimidazolin-1,3-diyl)bis(methylene)]-bis(benzonitrile). NMR (CDCl3) 7.65 (d,4), 7.4 (d,4), 4.45 (s,4), 3.2 (s,4) ppm.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05726198 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-b8ac393b893c42cfb6d34015ef8c6939 |
| 出典メモ | uspto-grants-1998_03 |