4-Methylpyridine → 1,1'-{Disulphanediylbis[ethane-2,1-diylimino(2-oxoethane-2,1-diyl)]}bis(4-methylpyridinium)dichloride

https://huagongshe.com/ja/reaction/1664084

関与物質

役割	名称	HCID	仕込み量
反応物	4-Methylpyridine	HCID 7963	—
反応物	N,N'-(disulfanediyldiethane-2,1-diyl)bis(2-chloroacetamide)	HCID 20525005	—
溶媒	N-methyl-2-pyrrolidone	HCID 13387	—
生成物	1,1'-{Disulphanediylbis[ethane-2,1-diylimino(2-oxoethane-2,1-diyl)]}bis(4-methylpyridinium)dichloride	HCID 86632282	—

反応条件

温度	80 °C

反応手順

6.1 g of N,N′-(disulphanediyldiethane-2,1-diyl)bis(2-chloroacetamide) and 4.5 g of 4-picoline are dissolved in 50 ml of NMP and the solution is heated at 80° C. for 19 hours. After the mixture has been cooled, 9.2 g of salts are recovered by successive precipitations from acetone and drying under vacuum. The analyses show that the product conforms. 1H NMR (400 MHz, D2O): 2.61 (s, 6H), 2.82 (t, 4H), 3.56 (t, 4H), 5.31 (s, 4H), 7.85 (d, 4H), 8.51 (d, 4H).

情報源と証拠

DOI	10.6084/m9.figshare.5104873.v1
特許番号	US08038731B2
出典データセット	uspto-grants-2011_10
ORD ID	ord-337e6113ee1f4c96aaabfdc4de507f94
出典メモ	uspto-grants-2011_10