Ammonia hydroxide → HCID 178446159、化合物
反応式
CS[C:3]1[N:11]([CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[C:10]2[N:9]=[CH:8][NH:7][C:6]=2[C:5](=[O:17])[N:4]=1.[OH-].[NH3:19]>>[NH:19]=[C:3]1[N:11]([CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[C:10]2[N:9]=[CH:8][NH:7][C:6]=2[C:5](=[O:17])[NH:4]1参加物
3
反応条件
- 温度
- 100 °C
実験手順
2-(Methylthio)-3-pentyl-3,7-dihydro-6H-purin-6-one (5.0 g, 0.020 mol) was mixed with 100 ml of 28% ammonia hydroxide in a seal tube. The mixture was stirred at 100° C. for 4 days. After cooling to room temperature, the solid was filtered and dried to yield the desired product (3.0 g, 68%). LCMS calculated for C10H16N5O (M+H): 222.1. found: 222.1.
後処理
- temperatureAfter cooling to room temperature
- filtrationthe solid was filtered
- customdried
出典と根拠
- ORDレコード
- ord-271cc3c13b3a4a0daa091460f7943ec4
- 出典データセット
- uspto-grants-2011_10
- 特許番号
- US08039478B2
反応ノート
読み込み中…