関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Selenium Dioxide | HCID 24007 | — |
| 反応物 | 2',5'-Dimethoxyacetophenone | HCID 70991 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | (2,5-Dimethoxyphenyl)-2-oxoacetaldehyde | HCID 81761435 | — |
反応手順
A mixture of 3.66 g (33 mmol) of selenium dioxide, 1 ml of water and 25 ml of dioxane is heated to 60° C. 5.4 g (30 mmol) of 2′,5′-dimethoxyacetophenone are added and the mixture is refluxed for 16 hours. The solvents are evaporated off (orange-coloured oil; 6 g) and the product obtained is purified by flash chromatography (dichloromethane) (3.1 g of yellow oil; 53%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07737176B2 |
|---|
| 出典データセット | uspto-grants-2010_06 |
|---|
| ORD ID | ord-0470c3e2d8ff4445b1914697fcfa1232 |
|---|
| 出典メモ | uspto-grants-2010_06 |
|---|
