4-Methoxypyridine-3-boronic acid → 4-amino-N-cyclobutyl-8-(4-methoxypyridin-3-yl)cinnoline-3-carboxamide

反応式

[CH3:20][O:21][c:22]1[c:23]([B:28]([OH:29])[OH:30])[cH:24][n:25][cH:26][cH:27]1.[NH2:1][c:2]1[c:3]([C:13](=[O:14])[NH:15][CH:16]2[CH2:17][CH2:18][CH2:19]2)[n:4][n:5][c:6]2[c:7]([Br:12])[cH:8][cH:9][cH:10][c:11]12>>[NH2:1][c:2]1[c:3]([C:13](=[O:14])[NH:15][CH:16]2[CH2:17][CH2:18][CH2:19]2)[n:4][n:5][c:6]2[c:7](-[c:23]3[c:22]([O:21][CH3:20])[cH:27][cH:26][n:25][cH:24]3)[cH:8][cH:9][cH:10][c:11]12

参加物

反応物 2

HCID 27625564-Methoxypyridine-3-boronic acid

HCID 672284794-amino-8-bromo-N-cyclobutyl-cinnoline-3-carboxamide

生成物 1

HCID 251834144-amino-N-cyclobutyl-8-(4-methoxypyridin-3-yl)cinnoline-3-carboxamide

出典と根拠

ORDレコード: ord-3b47b8a4c64147e88a6fc3add96a7870
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…