Hydroquinone → Malathion

HRID 1665879

反応式

HRID 1665879 の反応式
[CH3:1][O:2][P:3](=[S:7])([O:5][CH3:6])[SH:4].[C:8]([O:17][CH2:18][CH3:19])(=[O:16])/[CH:9]=[CH:10]\[C:11]([O:13][CH2:14][CH3:15])=[O:12].C1(C=CC(O)=CC=1)O>>[CH3:19][CH2:18][O:17][C:8]([CH2:9][CH:10]([S:7][P:3]([O:5][CH3:6])([O:2][CH3:1])=[S:4])[C:11]([O:13][CH2:14][CH3:15])=[O:12])=[O:16]

参加物

4

反応物 3

HCID 785HydroquinoneHCID 12959O,O-dimethyl phosphorodithioateHCID 5271566Diethyl Maleate

生成物 1

HCID 4004Malathion

反応条件

温度
55 °C

実験手順

The aqueous solution of dimethyldithiophosphoric acid prepared in Example 1 was combined with diethyl maleate (1.33 kg) and hydroquinone (3.3 g), and the resulting two-phase mixture was heated for 8 h at 53-57° C. under nitrogen atmosphere. The two-phase mixture was cooled to 22-30° C., and the phases were separated. The organic phase was washed with water (2×1 kg) to afford crude malathion (1.86 kg) containing at least about 30% (w/w) diethyl fumarate.

後処理

  1. temperatureThe two-phase mixture was cooled to 22-30° C.
  2. customthe phases were separated
  3. washThe organic phase was washed with water (2×1 kg)

出典と根拠

ORDレコード
ord-8180e9885e4f485d802f13bdd3d5f7e6
出典データセット
uspto-grants-2011_10
特許番号
US08039657B2

関連ノート

読み込み中…