Water → HCID 86629543、化合物
反応式
[CH3:1][S:2](Cl)(=[O:4])=[O:3].[Cl:6][C:7]1[CH:8]=[C:9]([CH:16]=[C:17]([Cl:19])[CH:18]=1)[CH:10]([OH:15])[C:11]([O:13][CH3:14])=[O:12].C(N(CC)CC)C.O>ClCCl>[Cl:6][C:7]1[CH:8]=[C:9]([CH:10]([O:15][S:2]([CH3:1])(=[O:4])=[O:3])[C:11]([O:13][CH3:14])=[O:12])[CH:16]=[C:17]([Cl:19])[CH:18]=1参加物
6
実験手順
Methanesulfonyl chloride (9.3 g) was added at 0° C. to a solution of methyl 3,5-dichloromandelate (19.0 g) and triethylamine (8.2 g) in dichloromethane (150 ml). After the addition, the mixture was stirred at room temperature for 3 hours, after which water (150 ml) was carefully added. The organic phase was separated, dried and concentrated to dryness, giving methyl 2-(3,5-dichlorophenyl)-2-mesyloxy-acetate (23.6 g) as an oil.
後処理
- additionAfter the addition
- customThe organic phase was separated
- customdried
- concentrationconcentrated to dryness
出典と根拠
- ORDレコード
- ord-4f8f5d69a3ae4440ae955a08aa4a95d3
- 出典データセット
- uspto-grants-2011_10
- 特許番号
- US08044067B2
反応ノート
読み込み中…